Anti-NSUN7 Antibody Picoband® 31.0550 Vervoeging

Predicted to enable RNA binding activity and methyltransferase activity. Predicted to be involved in RNA methylation. Predicted to act upstream of or within flagellated sperm motility and sperm mitochondrion organization.

NSUN7; Putative methyltransferase NSUN7; EC 2.1.1.-; NOL1/NOP2/Sun domain family member 7

NSUN7

79730

Q8NE18

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human NSUN7 recombinant protein (Position: D83-Q457) . Human NSUN7 shares 79.2% amino acid (aa) sequence identity with mouse NSUN7.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Harris, T., Marquez, B., Suarez, S., Schimenti, J. Sperm motility defects and infertility in male mice with a mutation in Nsun7, a member of the Sun domain-containing family of putative RNA methyltransferases. Biol. Reprod. 77: 376-382, 2007. 2. Khosronezhad, N., Hosseinzadeh Colagar, A., Mortazavi, S. M. The Nsun7 (A11337) -deletion mutation, causes reduction of its protein rate and associated with sperm motility defect in infertile men. J. Assist. Reprod. Genet. 32: 807-815, 2015. 3. Ren, H. Y., Zhong, R., Ding, X. P., Chen, Z. Y., Jing, Y. L. Investigation of polymorphisms in exon7 of the NSUN7 gene among Chinese Han men with asthenospermia. Genet. Molec. Res. 14: 9261-9268, 2015.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

81 kDa

6

NOP2/Sun RNA methyltransferase family member 7

Putative methyltransferase NSUN7

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.