Anti-NTMT1 Antilichaam

Boster Bio Anti-NTMT1 Antibody catalog # A10023. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

N-terminal Xaa-Pro-Lys N-methyltransferase 1;2.1.1.244

NTMT1

Q9BV86

Human, Mouse, Rat

Recombinant full length Human NTMT1.

WB, IF

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation (PubMed:24090352) . Catalyzes the trimethylation of the N-terminal Gly in CENPA (after removal of Met-1) . Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A10023

25387 MW

N-terminal Xaa-Pro-Lys N-methyltransferase 1

Nucleus

N-terminal Xaa-Pro-Lys N-methyltransferase 1

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2