Anti-Nuclear receptor ROR-beta RORB Antilichaam

Boster Bio Anti-Nuclear receptor ROR-beta RORB Antibody catalog # A09711. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Nuclear receptor ROR-beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; Retinoid-related orphan receptor-beta; RORB; NR1F2, RZRB

RORB

Q92753

Human, Mouse, Rat

Synthesized peptide derived from human protein at AA range: 210-290

WB, ELISA

RORB antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/mL

Liquid

Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09711

53220 MW

Nuclear receptor ROR-beta

Nucleus

Nuclear receptor ROR-beta

IgG

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.