Anti-nucleoporine p62 (N-terminaal gebied) Antilichaam

Active transport of proteins and RNA into and out of the nucleus occurs via the nuclear pore complex (NPC) . The NPC is formed by a multiprotein complex that includes nucleoporin proteins. Specific nuclear localization sequences found in proteins target proteins for active transport into the nucleus through the NPC. Nucleoporin p62 is the best characterized member of the family of nucleoporins found in the NPC. A tightly associated complex is formed by p62 and two other nucleoporins, p54 and p58. p54 binds to a carboxy-terminal coiled-coil domain of p62 and p58 binds to a dimer of p54. The amino-terminal domain of p62 contains a series of XFXFX repeats and is joined to the coiled-coil domain by a threonine-rich linker segment. The major role of p62 is maintenance of the structural integrity of NPCs.

Our Nucleoporin p62 (N-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects chicken, human, mouse, and rat Nucleoporin p62 (N-terminal region) and is protein a purified. It is great for use in ELISA, WB, ICC.

Our Nucleoporin p62 (N-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects chicken, human, mouse, and rat Nucleoporin p62 (N-terminal region) and is Protein A purified. It is great for use in WB, ICC.

NUP62

NUP62

P37198

Chicken, Human, Mouse, and Rat

Clone M436 was generated from a recombinant protein containing amino acid residues in the N-terminal region of human nucleoporin p62. This sequence has high homology to similar regions in rat, mouse, and chicken nucleoporin p62.

Nucleoporin p62 (N-terminal region)

M436

Unconjugated

ELISA, WB, ICC

Apoptosis, Cell Signaling, Wnt Signaling, Transporter Proteins

Protein A Purified

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

GOmAb

62

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Blue Ice

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Protein A purified culture supernatant.

1:500

This antibody detects a 62 kDa* protein corresponding to the apparent molecular mass of nucleoporin p62 on SDS-PAGE immunoblots of human HeLa and rat A7r5 cells. In immunocytochemistry, anti-Nucleoporin p62 specifically stains nuclei and nuclear envelope in paraformaldehyde fixed and NP-40 permeabilized cells.

1:50

Western blots performed on each lot.

Mouse

Liquid

IgG2b

Human

Quality Control: WB

AB_3068477