Anti-nucleostemin/GNL3 Antibody Picoband® fluoro647 Vervoeging

Guanine nucleotide-binding protein-like 3, also known as nucleostemin, is a protein that in humans is encoded by the GNL3 gene. The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.

CD48 antigen; B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD48; CD48; BCM1, BLAST1

GNL3

26354

Q9BVP2

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human Nucleostemin/GNL3 recombinant protein (Position: R45-V549) .

Flow Cytometry

Cell Type Markers, Immunology

Immunogen affinity purified.

Liquid

Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.

1. Charpentier, A. H., Bednarek, A. K., Daniel, R. L., Hawkins, K. A., Laflin, K. J., Gaddis, S., MacLeod, M. C., Aldaz, C. M. Effects of estrogen on global gene expression: identification of novel targets of estrogen action. Cancer Res. 60: 5977-5983, 2000. 2. Dai, M.-S., Sun, X.-X., Lu, H. Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2. Molec. Cell. Biol. 28: 4365-4376, 2008. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 6/29/2012.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

27683 MW

6

CD48 antigen

Cell membrane ; Lipid-anchor, GPI-anchor .

CD48 antigen

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.