Anti-OAS2 Antibody Picoband® 0,00647 Vervoeging

2'-5'-oligoadenylate synthetase 2 is an enzyme that in humans is encoded by the OAS2 gene. Enables 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Involved in defense response to virus; regulation of lactation; and type I interferon signaling pathway. Acts upstream of or within RNA catabolic process; interleukin-27-mediated signaling pathway; and response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol; membrane; and nucleoplasm. Is expressed in embryo. Orthologous to human OAS2 (2'-5'-oligoadenylate synthetase 2) .

Oas2; oasl11; 2'-5'-oligoadenylate synthase 2; (2-5'oligo (A synthase 2; 2-5A synthase 2; EC 2.7.7.84; 2',5'-oligoadenylate synthetase-like 11

OAS2

246728

E9Q9A9

Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived mouse OAS2 recombinant protein (Position: H35-K742) . Mouse OAS2 shares 62.4% and 77.5% amino acid (aa) sequence identity with human and rat ATF5, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Hovanessian, A. G., Laurent, A. G., Chebath, J., Galabru, J., Robert, N., Svab, J. Identification of 69-kd and 100-kd forms of 2-5A synthetase in interferon-treated human cells by specific monoclonal antibodies. EMBO J. 6: 1273-1280, 1987. 2. Hovnanian, A., Rebouillat, D., Mattei, M.-G., Levy, E. R., Marie, I., Monaco, A. P., Hovanessian, A. G. The human 2-prime,5-prime-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40-kDa forms. Genomics 52: 267-277, 1998. 3. Marie, I., Galabru, J., Svab, J., Hovanessian, A. G. Preparation and characterization of polyclonal antibodies specific for the 69 and 100 k-dalton forms of human 2-5A synthetase. Biochem. Biophys. Res. Commun. 160: 580-587, 1989.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

82 kDa

6

2'-5' oligoadenylate synthetase 2

2'-5'-oligoadenylate synthase 2

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.