Anti-OAT1/SLC22A6 Antibody Picoband® fluoro488 Vervoeging

The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene.

SLC22A6

9356

Q4U2R8

Human

E.coli-derived human OAT1/SLC22A6 recombinant protein (Position: R286-L563) . Human SLC22A6 shares 82% and 83.8% amino acid (aa) sequence identity with mouse and rat SLC22A6, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Bahn, A., Prawitt, D., Buttler, D., Reid, G., Enklaar, T., Wolff, N. A., Ebbinghaus, C., Hillemann, A., Schulten, H.-J., Gunawan, B., Fuzesi, L., Zabel, B., Burckhardt, G. Genomic structure and in vivo expression of the human organic anion transporter 1 (hOAT1) gene. Biochem. Biophys. Res. Commun. 275: 623-630, 2000. 2. Lu, R., Chan, B. S., Schuster, V. L. Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. Am. J. Physiol. 276: F295-F303, 1999. 3. Race, J. E., Grassl, S. M., Williams, W. J., Holtzman, E. J. Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3) . Biochem. Biophys. Res. Commun. 255: 508-514, 1999.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

62 kDa

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.