Anti-OAT2/SLC22A7 Antibody Picoband® fluoro488 Vervoeging

Solute carrier family 22 member 7, also called SLC22A7 or OAT2 is a protein that in humans is encoded by the SLC22A7 gene. This gene is mapped to 6p21.1. The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. This gene transports prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate.

Transcription factor MafA; Pancreatic beta-cell-specific transcriptional activator; RIPE3b1 factor; V-maf musculoaponeurotic fibrosarcoma oncogene homolog A; MAFA

SLC22A7

10864

Q9Y694

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human OAT2/SLC22A7 recombinant protein (Position: L33-N548) .

Preferentially expressed in regulatory T-cells (Tregs) .

Flow Cytometry

Signal Transduction

Immunogen affinity purified.

Liquid

Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence.

1. Kok, L. D., Siu, S. S., Fung, K. P., Tsui, S. K., Lee, C. Y., Waye, M. M. Assignment of liver-specific organic anion transporter (SLC22A7) to human chromosome 6 bands p21.2-p21.1 using radiation hybrids. Cytogenet. Cell Genet. 88: 76-77, 2000. 2. Sun, W., Wu, R. R., van Poelje, P. D., Erion, M. D. Isolation of a family of organic anion transporters from human liver and kidney. Biochem. Biophys. Res. Commun. 283: 417-422, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

39411 MW

6

MAF bZIP transcription factor A

Nucleus.

Zinc finger protein Helios

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.