Anti-OIT3 Antibody Picoband® fluoro488 Vervoeging

This gene was identified due to its downregulation in hepatocarcinomas. The encoded protein may be involved in liver development and function.

Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/I; Histone H3/j; Histone H3/k; Histone H3/l; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; H3FJ

OIT3

170392

Q8WWZ8

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human OIT3 recombinant protein (Position: D43-L281) .

Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Flow Cytometry

DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling, RNA Processing

Immunogen affinity purified.

Liquid

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

1. Xu, Z.-G., Du, J.-J., Zhang, X., Cheng, Z.-H., Ma, Z.-Z., Xiao, H.-S., Yu, L., Wang, Z.-Q., Li, Y.-Y., Huo, K.-K., Han, Z.-G. A novel liver-specific zona pellucida domain containing protein that is expressed rarely in hepatocellular carcinoma. Hepatology 38: 735-744, 2003. 2. Yang, H., Wu, C., Zhao, S., Guo, J. Identification and characterization of D8C, a novel domain present in liver-specific LZP, uromodulin and glycoprotein 2, mutated in familial juvenile hyperuricaemic nephropathy. FEBS Lett. 578: 236-238, 2004.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Histone cluster 1 H3 family member a/b/c/d/e/f/g/h/i/j

Cytoplasm.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.