Anti-OLFML2B Antibody Picoband® fluoro550 Vervoeging

This gene encodes an olfactomedin domain-containing protein. Most olfactomedin domain-containing proteins are secreted glycoproteins.

Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1; KBTBD2; BKLHD1; KIAA1489

OLFML2B

25903

Q68BL8

Human

No cross-reactivity with other proteins.

E.coli-derived human OLFML2B recombinant protein (Position: I23-N671) .

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Flow Cytometry

Cell Biology

Immunogen affinity purified.

Liquid

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

1. Liu, J. , Liu, Z. , Zhang, X. , Gong, T. , & Yao, D. . (2019) . Bioinformatic exploration of olfml2b overexpression in gastric cancer base on multiple analyzing tools. BMC Cancer, 19 (1), 1-10. 2. Nolte, I. M. , Wallace, C. , Newhouse, S. J. , Waggott, D. , Fu, J. , & Soranzo, N. , et al. (2009) . Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. PLoS ONE, 4 (7), e6138. 3. Reiner, A. , Beleza, S. , Franceschini, N. , Auer, P. , Robinson, J. , & Kooperberg, C. , et al. (2012) . Genome-wide association and population genetic analysis of c-reactive protein in african american and hispanic american women. The American Journal of Human Genetics, 91 (3), 502-512.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

24145 MW

6

Kelch repeat and BTB domain containing 2

Cul3-RING ubiquitin ligase complex.

Transmembrane protein 240

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.