Anti-Orexin-A-antilichaam

FUNCTION: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity. SUBCELLULAR LOCATION: Endoplasmic reticulum; rough endoplasmic reticulum. Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. SIMILARITY: Belongs to the orexin family.

Our Anti-Orexin-A rabbit polyclonal primary antibody detects bovine, and rat Orexin-A , and is whole serum. It is validated for use in IHC-Frozen.

Our Anti-Orexin-A rabbit polyclonal primary antibody detects bovine, and rat Orexin-A, and is whole serum. It is validated for use in IHC-Frozen.

Orexin-A; Hypocretin-1; Hcrt1

P56717

Bovine, and Rat

A synthetic peptide (CRLYELLHGAGNHAAGILTL) as part of Bovine Orexin A (aa: 14-33) conjugated to KLH has been used as the immunogen.

Orexin-A

Unconjugated

IHC-Frozen

Whole serum

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

1:1000-1:2000

The specificity for this antiserum has been confirmed by immunohistochemistry on rat brain and the results reflect the current literature. This antibody is known to react with rat Orexin A.

Rabbit

Lyophilized

Mixed

Bovine