Anti-OSBPL2 Antibody Picoband® fluoro488 Vervoeging

Oxysterol-binding protein-related protein 2 is a protein that in humans is encoded by the OSBPL2 gene. This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

OSBPL2

9885

Q9H1P3

Human, Mouse, Rat

E.coli-derived human OSBPL2 recombinant protein (Position: E6-Y480) . Human OSBPL2 shares 89% amino acid (aa) sequence identity with mouse OSBPL2.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Jaworski, C. J., Moreira, E., Li, A., Lee, R., Rodriguez, I. R. A family of 12 human genes containing oxysterol-binding domains. Genomics 78: 185-196, 2001. 2. Laitinen, S., Olkkonen, V. M., Ehnholm, C., Ikonen, E. Family of human oxysterol binding protein (OSBP) homologues: a novel member implicated in brain sterol metabolism. J. Lipid Res. 40: 2204-2211, 1999. 3. Lehto, M., Laitinen, S., Chinetti, G., Johansson, M., Ehnholm, C., Staels, B., Ikonen, E., Olkkonen, V. M. The OSBP-related protein family in humans. J. Lipid Res. 42: 1203-1213, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

55 kDa

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.