Anti-OSBPL5 Antibody Picoband® HRP Vervoeging

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified.

OSBPL5; KIAA1534; OBPH1; ORP5; Oxysterol-binding protein-related protein 5; ORP-5; OSBP-related protein 5; Oxysterol-binding protein homolog 1

OSBPL5

114879

Q9H0X9

Human

No cross-reactivity with other proteins

E.coli-derived human OSBPL5 recombinant protein (Position: R26-K879) . Human OSBPL5 shares 84.4% amino acid (aa) sequence identity with mouse OSBPL5.

WB, IHC, ELISA

Immunogen affinity purified.

Liquid

1. Chung, J., Torta, F., Masai, K., Lucast, L., Czapla, H., Tanner, L. B., Narayanaswamy, P., Wenk, M. R., Nakatsu, F., De Camilli, P. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts. Science 349: 428-432, 2015. 2. Higashimoto, K., Soejima, H., Yatsuki, H., Joh, K., Uchiyama, M., Obata, Y., Ono, R., Wang, Y., Xin, Z., Zhu, X., Masuko, S., Ishino, F., Hatada, I., Jinno, Y., Iwasaka, T., Katsuki, T., Mukai, T. Characterization and imprinting status of OBPH1/Obph1 gene: implications for an extended imprinting domain in human and mouse. Genomics 80: 575-584, 2002. Note: Erratum: Genomics 81, 346 only, 2003. 3. Jaworski, C. J., Moreira, E., Li, A., Lee, R., Rodriguez, I. R. A family of 12 human genes containing oxysterol-binding domains. Genomics 78: 185-196, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

99 kDa

Oxysterol binding protein like 5

Oxysterol-binding protein-related protein 5

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.