Anti-OSBPL9 Antibody Picoband®

Oxysterol binding protein-like 9 is a protein that in humans is encoded by the OSBPL9 gene. This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12.

Boster Bio Anti-OSBPL9 Antibody Picoband® catalog # A09498-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Mediator of RNA polymerase II transcription subunit 20; Mediator complex subunit 20; TRF-proximal protein homolog; hTRFP; MED20; TRFP

OSBPL9

114883

Q96SU4

Human, Mouse

No cross-reactivity with other proteins.

E.coli-derived human OSBPL9 recombinant protein (Position: D27-K652) .

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

WB, ICC, IF, Flow Cytometry, ELISA

Epigenetics and Nuclear Signaling, Mediator Complex, Transcription

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

1. Jaworski, C. J., Moreira, E., Li, A., Lee, R., Rodriguez, I. R. A family of 12 human genes containing oxysterol-binding domains. Genomics 78: 185-196, 2001. 2. Lehto, M., Laitinen, S., Chinetti, G., Johansson, M., Ehnholm, C., Staels, B., Ikonen, E., Olkkonen, V. M. The OSBP-related protein family in humans. J. Lipid Res. 42: 1203-1213, 2001. 3. Ngo, M., Ridgway, N. D. Oxysterol binding protein-related protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function. Molec. Biol. Cell 20: 1388-1399, 2009.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A09498-1

95 kDa

6

CD72 molecule

Nucleus .

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.