Anti-OXSM Antibody Picoband® 0,00647 Vervoeging

This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.

Mediator of RNA polymerase II transcription subunit 9; Mediator complex subunit 9; MED9; MED25

OXSM

54995

Q9NWU1

Human, Rat

No cross-reactivity with other proteins.

E.coli-derived human OXSM recombinant protein (Position: M1-E431) .

Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Flow Cytometry

Epigenetics and Nuclear Signaling, Mediator Complex, Pol II Transcription, Polymerase Associated Factors, RNA Polymerase, Transcription

Immunogen affinity purified.

Liquid

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

1. Zhang, L., Joshi, A. K., Hofmann, J., Schweizer, E., Smith, S. Cloning, expression, and characterization of the human mitochondrial beta-ketoacyl synthase. J. Biol. Chem. 280: 12422-12429, 2005.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Mediator complex subunit 9

Nucleus .

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.