Anti-p140Cap SRCIN1 Antilichaam

Boster Bio Anti-p140Cap SRCIN1 Antibody catalog # A08110. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

SRC kinase signaling inhibitor 1; SNAP-25-interacting protein; SNIP; p130Cas-associated protein; p140Cap; SRCIN1; KIAA1684, P140

SRCIN1

Q9C0H9

Human, Mouse, Rat

The antiserum was produced against synthesized peptide derived from human SNIP. AA range:811-860

Expressed in some primary breast carcinomas where its presence is significantly associated with increased tumor size. Not detected in normal breast tissue. .

WB, ELISA

Immunogen affinity purified

1 mg/mL

Liquid

Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A08110

112453 MW

SRC kinase signaling inhibitor 1

Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, axon . Cell projection, dendrite . Cell junction, synapse . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions. Strongly expressed in axons and dendrites of the CA1 and CA3 hippocampal regions and of the dentate gyrus. Detected in both presynapses and postsynapses and in postsynaptic density fractions.

IgG

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.