Anti-p53 Monoklonale Antilichaam (Kloon:IHC053)

P53, also known as tumor protein 53 or TP53, is a tumor suppressor and transcription factor that functions in a number of anti-cancer activities including DNA repair, cell-cycle arrest, and apoptosis in response to DNA damage or other stressors. Mutations in p53 are linked to a number of malignant tumors, including those of the breast, ovarian, bladder, colon, lung, and melanoma. Anti-p53 staining has been used to detect intratubular germ cell neoplasia, and also to distinguish between uterine serous carcinoma and endometrioid carcinoma.

TP53||P53

TP53

7157

P04637

Human

Recombinant Human p53

IHC053

IHC

Protein A/G Chromatography

Purified

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and

Store at 2°C - 8°C. Do not freeze.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

Mouse IgG2b