Anti-PAX-8 Monoklonale antilichamen (Kloon:IHC008)

PAX-8 is a member of the paired box (PAX) family of transcription factors, which are key regulators in early development. This protein plays a role in development of thyroid follicular cells and the expression of thyroid-specific genes, with mutations in the PAX-8 gene linked to thyroid follicular carcinomas, atypical thyroid adenomas, and thyroid dysgenesis. The PAX-8 protein is expressed in simple ovarian inclusion cysts and non-ciliated mucosal cells of the fallopian tubes, but is absent from normal ovarian surface epithelial cells. PAX-8 is also not expressed in normal lung or lung carcinomas.

PAX8

PAX8

7849

Q06710

Human

Recombinant Human PAX8

IHC008

IHC

Protein A/G Chromatography

Purified

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and

Store at 2°C - 8°C. Do not freeze.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

Mouse IgG2a