Anti-Peroxiredoxin-6 (NSGPx) Antilichaam

FUNCTION: Involved in redox regulation of the cell. Can reduce H (2) O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. SUBUNIT: Homotetramer. SUBCELLULAR LOCATION: Cytoplasm. Lysosome. Also found in lung secretory organelles. MISCELLANEOUS: The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin . MISCELLANEOUS: Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO (3) H) upon oxidative stress. SIMILARITY: Belongs to the ahpC/TSA family. Rehydrin subfamily.

Our Anti-Peroxiredoxin-6 (NSGPx) rabbit polyclonal primary antibody detects human, mouse, and rat Peroxiredoxin-6 (NSGPx), and is whole serum. It is validated for use in ELISA, ICC, IHC-Frozen, IHC-Paraffin-embedded, WB.

Our Anti-Peroxiredoxin-6 (NSGPx) rabbit polyclonal primary antibody detects human, mouse, and rat Peroxiredoxin-6 (NSGPx), and is whole serum. It is validated for use in ELISA, ICC, IHC-Frozen, IHC-Paraffin-embedded, WB.

Non-selenium glutathione peroxidase; antioxidant protein 2; 1-Cys peroxiredoxin; 1-Cys PRX; Acidic calcium-independent phospholipase A2; NSGPx; Thiol-specific antioxidant protein; Prdx6; Aipla2; Aop2; Tsa

O35244

Human, Mouse, and Rat

Rat recombinant Peroxiredoxin-6. The sequence is homologous in human and mouse peroxiredoxin-6.

Peroxiredoxin-6 (NSGPx)

Unconjugated

ELISA, ICC, IHC-Frozen, IHC-Paraffin-embedded, WB

Whole serum

For research use only.

25°C (ambient)

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles. Glycerol (1:1) may be added for an additional stability.

1:1000-1:4000

1:100-1:1000

This antibody has been shown to be specific for Peroxiredoxin-6 protein. Rat, human and mouse, other species have not yet been tested.

Rabbit

Lyophilized

Mixed

Human