Anti-PFDN5 Konijn Monoklonale Antilichaam

Boster Bio Anti-PFDN5 Rabbit Monoclonal Antibody catalog # M09908. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Cysteine protease ATG4C;3.4.22.-; AUT-like 3 cysteine endopeptidase; Autophagin-3; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C; ATG4C; APG4C, AUTL1, AUTL3

PFDN5

5204

Q99471

Human, Mouse, Rat

A synthesized peptide derived from human PFDN5

Clone: 18P17

Highly expressed in skeletal muscle, heart, liver and testis. .

WB, IHC, IP

Metabolism Processes, Oncoproteins, Oncoproteins/Suppressors, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity) . Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M09908

52497 MW

60 kDa

Cysteine protease ATG4C

Cytoplasm .

T-cell surface glycoprotein CD3 zeta chain

IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.