Anti-PGC1 beta PPARGC1B Monoklonale antilichamen

Boster Bio Anti-PGC1 beta PPARGC1B Monoclonal Antibody catalog # M02933. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Integrin-linked protein kinase;2.7.11.1;59 kDa serine/threonine-protein kinase; ILK-1; ILK-2; p59ILK; ILK; ILK1, ILK2

PPARGC1B

133522

Q86YN6

Human, Mouse, Rat

A synthesized peptide derived from human PGC1 beta

Clone: AEOI-16

Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.

WB, IP

Atherosclerosis, Cancer, Cardiovascular, Co-Activators/Co-Repressors, Diabetes, Diabetes-associated, Energy Metabolism, Energy Transfer Pathways, Epigenetics and Nuclear Signaling, Fatty Acid Oxidation, Fatty Acids, Heart Disease, Lipid and Lipoprotein Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Nuclear Receptors, Nuclear Signaling Pathways, Obesity, Pathways and Processes, Redox Metabolism, Signal Transduction, Transcription

Affinity-chromatography

0.5mg/ml

Liquid

Receptor-proximal protein kinase regulating integrin- mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02933

51419 MW

113 kDa

Integrin-linked protein kinase

Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium . Cytoplasm, myofibril, sarcomere.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.