Anti-PGP Antibody Picoband® 31.0550 Vervoeging

PGP (phosphoglycolate phosphatase) belongs to the HAD-like hydrolase superfamily. It is an essential intermediate in the biosynthetic pathway of cardiolipin and a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. PGP catalyzes the formation of phosphatidylglycerol from phosphatidylglycerophosphate.

Protein C-ets-1; p54; ETS1; EWSR2

PGP

283871

A6NDG6

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human PGP recombinant protein (Position: M1-G321) .

Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney. .

Flow Cytometry

Cancer, Cardiogenesis, Cardiovascular, Domain Families, Epigenetics and Nuclear Signaling, Oncoproteins, Oncoproteins/Suppressors, Transcription, Transcription Factors, Transcription Factors/Regulators

Immunogen affinity purified.

Liquid

Transcription factor. ly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. .

1. Amorim, A., Siebert, G., Ritter, H., Kompf, J. Formal genetics of phosphoglycolate phosphate (PGP) : investigation on 272 mother-child pairs. Hum. Genet. 53: 419-420, 1980. 2. Bale, S. J., Chakravarti, A., Ferrell, R. E., Spence, M. A. Possible heterogeneity in the phosphoglycolate phosphatase (PGP) -haptoglobin alpha (HPA) linkage. Am. J. Hum. Genet. 36: 808-814, 1984. 3. Barker, R. F., Hopkinson, D. A. Genetic polymorphism of human phosphoglycolate phosphatase (PGP) . Ann. Hum. Genet. 42: 143-151, 1978.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

50408 MW

6

Protein C-ets-1

Cytoplasm . Nucleus . Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27. .

Protein C-ets-1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.