Anti-Phospho-CrkII (Tyr221) Konijn Monoklonale Antilichaam

Boster Bio Anti-Phospho-CrkII (Tyr221) Rabbit Monoclonal Antibody catalog # P02533. Tested in WB, ICC/IF applications. This antibody reacts with Human.

Tyr221

Adapter molecule crk; Proto-oncogene c-Crk; p38; CRK

CRK

1398

P46108

Human

A synthesized peptide derived from human Phospho-CrkII (Tyr221)

Clone: FDE-3

Expressed in brain, and to a lesser extent in lung, kidney and testis.

WB, ICC, IF

Adapters, Cancer, Cytoplasmic, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=P02533

33831 MW

85 kDa

Adapter molecule crk

Cytoplasm . Cell membrane . Translocated to the plasma membrane upon cell adhesion. .

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.