Anti-Phospho-eIF4E (S209) Konijn Monoklonale Antilichaam

Boster Bio Anti-Phospho-eIF4E (S209) Rabbit Monoclonal Antibody catalog # P00135. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

S209

Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein; EIF4E; EIF4EL1, EIF4F

EIF4E

1977

P06730

Human, Mouse, Rat

A synthesized peptide derived from human Phospho-eIF4E (S209)

Clone: DBD-5

Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level) . .

WB, IHC, ICC, IF, IP

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing, Translation

Affinity-chromatography

0.5mg/ml

Liquid

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=P00135

25097 MW

70, 75 kDa

Eukaryotic translation initiation factor 4E

Cytoplasm, P-body . Cytoplasm .

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.