Anti-Phospho-FoxO3a (S253) Konijn Monoklonale Antilichaam

Boster Bio Anti-Phospho-FoxO3a (S253) Rabbit Monoclonal Antibody catalog # P00252. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

S253

Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1, FOXO3A

FOXO3

2309

O43524

Human, Mouse, Rat

A synthesized peptide derived from human FoxO3a

Clone: ECG-6

Ubiquitous. .

WB, IHC

Apoptosis, Associated Proteins, Cancer, Cell Biology, Co-Activators/Co-Repressors, Domain Families, Epigenetics and Nuclear Signaling, Forkhead Box, Hypoxia, Intracellular, Metabolism, Metabolism Processes, Nuclear Receptors, Nuclear Signaling Pathways, Oncoproteins, Oncoproteins/Suppressors, Pathways and Processes, Transcription, Transcription Factors

Affinity-chromatography

0.5mg/ml

Liquid

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=P00252

70 kDa

80-100 kDa

Forkhead box protein O3

Cytoplasm, cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors.

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.