Anti-Phospho-IRE1 (S724)

Boster Bio Anti-Phospho-IRE1 (S724) ERN1 Rabbit Monoclonal Antibody catalog # P00683. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

S724

Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a; Serine/threonine-protein kinase;2.7.11.1; Endoribonuclease;3.1.26.-; ERN1 ; IRE1

ERN1

81

O75460

Human, Mouse, Rat

A synthesized peptide derived from human Phospho-IRE1 (S724)

Clone: EGH-5

Ubiquitously expressed. High levels observed in pancreatic tissue. .

WB

Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=P00683

109735 MW

185 kDa

Serine/threonine-protein kinase/endoribonuclease IRE1

Endoplasmic reticulum membrane ; Single-pass type I membrane protein .

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.