Anti-Phospho-LAT (Y191) Konijn Monoklonale Antilichaam

Boster Bio Anti-Phospho-LAT (Y191) Rabbit Monoclonal Antibody catalog # P01654. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Y191

Linker for activation of T-cells family member 1;36 kDa phospho-tyrosine adapter protein; pp36; p36-38; LAT

LAT

27040

O43561

Human, Mouse, Rat

A synthesized peptide derived from human Phospho-LAT (Y191)

Clone: AOH-12

Expressed in thymus, T-cells, NK cells, mast cells and, at lower levels, in spleen. Present in T-cells but not B-cells (at protein level) . .

WB, IHC, ICC, IF, IP

Adapters, Adaptive Immunity, G Protein Signaling, Immunology, Non-CD, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins, T Cells, Transmembrane

Affinity-chromatography

0.5mg/ml

Liquid

Required for TCR (T-cell antigen receptor) - and pre-TCR- mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III) -mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=P01654

27930 MW

156 kDa

Linker for activation of T-cells family member 1

Cell membrane ; Single-pass type III membrane protein . Present in lipid rafts.

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.