Anti-Phospho-SMC1 (S957) Monoklonale Antilichaam
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Anti-Phospho-SMC1 (S957) Monoklonale Antilichaam

Catalog #: MP02148
Maat: 100 µL/Vial

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Documentatie

Technische Specificaties

Description

Boster Bio Anti-Phospho-SMC1 (S957) Monoclonal Antibody catalog # MP02148. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Phospho Site

S957

Synonyms

Red fluorescent protein eqFP611; GFP-like chromoprotein

Gene Name

SMC1A

Gene ID

8243

UniProt

Q14683

Host

• Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-SMC1 (S957) Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment.

Clonality

• Monoclonal

Clone

Clone: FCI-19

Tissue Specificity

Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC) . Levels rapidly diminish as soon as ESC's differentiate (at protein levels) . Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. .

Applications

WB, IHC, ICC, IF

Field of Research

Cell Biology, Cell Cycle, Cell Division

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Pigment protein. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product MSDS

https://www.bosterbio.com/msds?sku=MP02148

Calculated Molecular Weight

26053 MW

Observed Molecular Weight

15 kDa

Gene Name Synonym

Red fluorescent protein eqFP611

Subcellular Location

Lateral cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Colocalizes with CLDN7 at the lateral cell membrane and tight junction. .

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Beschrijving

Boster Bio Anti-Phospho-SMC1 (S957) Monoclonal Antibody catalog # MP02148. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Specificaties

ProductnaamAnti-Phospho-SMC1 (S957) Monoklonale Antilichaam
Categorie
Beschikbare grootte100 µL/Vial
CatalogusnummerMP02148