Anti-Phospholipide scramblase 3 PLSCR3 Antilichaam

Boster Bio Anti-Phospholipid scramblase 3 PLSCR3 Antibody catalog # A10575. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Phospholipid scramblase 3; PL scramblase 3; Ca (2+) -dependent phospholipid scramblase 3; PLSCR3

PLSCR3

Q9NRY6

Human, Mouse, Rat

Recombinant fusion protein of human PLSCR3 (NP_065093.2) .

Expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver.

WB, IHC, ICC, IF

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A10575

31648 MW

Phospholipid scramblase 3

Mitochondrion membrane

Phospholipid scramblase 3

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2