Anti-PHYHIPL Antibody Picoband® fluoro550 Vervoeging

Phytanoyl-CoA hydroxylase-interacting protein-like is an enzyme that in humans is encoded by the PHYHIPL gene. PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein-like), also known as phytanoyl-CoA hydroxylase-interacting protein-like, is a 376 amino acid protein that contains one fibronectin type-III domain and belongs to the PHYHIP family. Conserved in chimpanzee, canine, mouse, rat, chicken, zebrafish and Caenorhabditis elegans, PHYHIPL exists as three alternatively spliced isoforms. PHYHIPL is a down-regulated target of IRX1, a homeobox tumor suppressor gene linked to gastric carcinoma. PHYHIPL may also play a role in the development of the central system. The gene that encodes PHYHIPL maps to human chromosome 10q21.1.

PHYHIPL

84457

Q96FC7

Human, Mouse, Rat

E.coli-derived human PHYHIPL recombinant protein (Position: M1-D336) . Human PHYHIPL shares 97.3% and 96.7% amino acid (aa) sequence identity with mouse and rat PHYHIPL, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Fu, H., Ge, B., Chen, D., Wu, Y., Luo, Q., Li, X., ... & Tang, Q. (2019) . Phytanoyl-CoA 2-hydroxylase-interacting protein-like gene is a therapeutic target gene for glioblastoma multiforme. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 25, 2583. 2. Sugimoto, H., Horii, T., Hirota, J. N., Sano, Y., Shinoda, Y., Konno, A., ... & Sadakata, T. (2021) . The Ser19Stop single nucleotide polymorphism (SNP) of human PHYHIPL affects the cerebellum in mice. Molecular Brain, 14, 1-9. 3. Ying, H., Zheng, H., Scott, K., Wiedemeyer, R., Yan, H., Lim, C., ... & DePinho, R. A. (2010) . Mig-6 controls EGFR trafficking and suppresses gliomagenesis. Proceedings of the National Academy of Sciences, 107 (15), 6912-6917.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

42,40,6 kDa

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.