Anti-PI3 Kinase, p85 (C-terminaal gebied) Antilichaam

Phosphoinositide 3-kinase (PI3K) phosphorylates phosphatidylinositol (PI), PI-4-phosphate and PI-4,5-bisphosphate to catalyze the production of PI-3,4,5-triphosphate. Growth factors and hormones activate PI3K to coordinate various cellular events, such as cell growth, cell cycle entry, cell migration and cell survival. This PI3K activation is reversed by PTEN. In cancers caused by the loss of PTEN activity, PI3K is constituitively active and promotes cell proliferation. PI3Ks are composed of a catalytic subunit and a regulatory subunit. Various isoforms of the catalytic subunit (p110a, p110b and p110d) associate with regulatory subunits (p85a and p85b) with the exception of p110g which interacts with a unique p101 regulatory subunit.

Our PI3 Kinase, p85 (C-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects chicken, human, mouse, and rat PI3 Kinase, p85 (C-terminal region) and is protein a purified. It is great for use in ELISA, WB, ICC.

Our PI3 Kinase, p85 (C-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects chicken, human, mouse, and rat PI3 Kinase, p85 (C-terminal region) and is Protein A purified. It is great for use in WB, ICC.

PI3K

PIK3R1

P27986

Chicken, Human, Mouse, and Rat

Clone M253 was generated from a recombinant protein corresponding to amino acids in the C-terminal region of human PI3 Kinase α subunit. This region is homologous to similar regions in rat and mouse PI3 Kinase α subunit.

PI3 Kinase, p85 (C-terminal region)

M253

Unconjugated

ELISA, WB, ICC

Cell Signaling, Kinase Signaling, Oncoproteins

Protein A Purified

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

GOmAb

85

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Blue Ice

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Protein A purified culture supernatant.

1:1000

This antibody detects an 85 kDa* band corresponding to the p85 subunit of PI3 Kinase in western blots of human A431 and Jurkat cells.

1:100

Western blots performed on each lot.

Mouse

Liquid

IgG2a

Human

Quality Control: WB

AB_2165546