Anti-PIAP Antibody Picoband® fluoro594 Vervoeging

This gene encodes a ligand for the paired immunoglobin-like type 2 receptor alpha, and so may be involved in immune regulation. Alternate splicing results in multiple transcript variants encoding different proteins.

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

PIANP

196500

Q8IYJ0

Human

No cross-reactivity with other proteins

E.coli-derived human PIANP recombinant protein (Position: R56-L282) .

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Flow Cytometry

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Immunogen affinity purified.

Liquid

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

1. Evdokimov, K., Biswas, S., Adrian, M., Weber, J., Schledzewski, K., Winkler, M., Goerdt, S., Geraud, C. Proteolytic cleavage of LEDA-1/PIANP by furin-like proprotein convertases precedes its plasma membrane localization. Biochem. Biophys. Res. Commun. 434: 22-27, 2013. 2. Geraud, C., Schledzewski, K., Demory, A., Klein, D., Kaus, M., Peyre, F., Sticht, C., Evdokimov, K., Lu, S., Schmieder, A., Goerdt, S. Liver sinusoidal endothelium: a microenvironment-dependent differentiation program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1. Hepatology 52: 313-326, 2010. 3. Gross, M. B. Personal Communication. Baltimore, Md. 10/28/2014.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

64099 MW

6

RNA-binding protein 47

Nucleus .

Follicular dendritic cell secreted peptide

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.