Anti-PIP4K2B Antibody Picoband® HRP Vervoeging

The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.

PIP4K2B; PIP5K2B; Phosphatidylinositol 5-phosphate 4-kinase type-2 beta; EC 2.7.1.149; 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; PI (5P 4-kinase type II beta; PIP4KII-beta; PtdIns (5P-4-kinase isoform 2-beta

PIP4K2B

8396

P78356

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human PIP4K2B recombinant protein (Position: D116-K360) . Human PIP4K2B shares 98.8% and 97.6% amino acid (aa) sequence identity with mouse and rat PIP4K2B, respectively.

WB, IHC, ELISA

Immunogen affinity purified.

Liquid

1. Castellino, A. M., Parker, G. J., Boronenkov, I. V., Anderson, R. A., Chao, M. V. A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase. J. Biol. Chem. 272: 5861-5870, 1997. 2. Ciruela, A., Hinchliffe, K. A., Divecha, N., Irvine, R. F. Nuclear targeting of the beta isoform of type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its alpha-helix 7. Biochem. J. 346: 587-591, 2000. 3. Lamia, K. A. Personal Communication. Boston, Mass. 8/26/2004.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

47 kDa

Phosphatidylinositol-5-phosphate 4-kinase type 2 beta

Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4.