Anti-PIP5K1A Antibody Picoband® Biotin Conjugated

Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity and kinase binding activity. Involved in several processes, including activation of GTPase activity; focal adhesion assembly; and ruffle assembly. Located in several cellular components, including lamellipodium; nucleus; and ruffle membrane.

PIP5K1A; Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; PIP5K1-alpha; PtdIns (4P-5-kinase 1 alpha; EC 2.7.1.68; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; PIP5KIalpha

PIP5K1A

8394

Q99755

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human PIP5K1A recombinant protein (Position: I33-H562) . Human PIP5K1A shares 92.2% and 92.4% amino acid (aa) sequence identity with mouse and rat PIP5K1A, respectively.

WB, IHC, ELISA

Immunogen affinity purified.

Liquid

1. Ishihara, H., Shibasaki, Y., Kizuki, N., Wada, T., Yazaki, Y., Asano, T., Oka, Y. Type I phosphatidylinositol-4-phosphate 5-kinases: cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. J. Biol. Chem. 273: 8741-8748, 1998. 2. Loijens, J. C., Anderson, R. A. Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family. J. Biol. Chem. 271: 32937-32943, 1996. 3. Mellman, D. L., Gonzales, M. L., Song, C., Barlow, C. A., Wang, P., Kendziorski, C., Anderson, R. A. A PtdIns4,5P (2) -regulated nuclear poly (A) polymerase controls expression of select mRNAs. Nature 451: 1013-1017, 2008.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing.

63kDa

Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha

Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.