Anti-Plxdc2 Antilichaam

Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.

Boster Bio Anti-Plxdc2 Antibody (Catalog # A08798) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

TEM7R, TEM7R, UNQ2514/PRO6003, Plexin domain-containing protein 2, Tumor endothelial marker 7-related protein

PLXDC2

Q6UX71

Human, Mouse, Rat

Plxdc2 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human Plxdc2. The immunogen is located within amino acids 40 - 90 of Plxdc2.

Expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue.

ELISA, WB, IHC-P, IF

Homeostasis

Plxdc2 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

May play a role in tumor angiogenesis.

Plxdc2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A08798

59583 MW

Plexin domain containing 2

Membrane ; Single-pass type I membrane protein .

Plexin domain containing 2

IgG

Plxdc2 Antibody is supplied in PBS containing 0.02% sodium azide.