Anti-PMVK Antibody Picoband®

This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.

Boster Bio Anti-PMVK Antibody Picoband® catalog # A10103. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

PMVK

10654

Q15126

Human, Mouse, Rat

E.coli-derived human PMVK recombinant protein (Position: K22-L192) . Human PMVK shares 82.5% amino acid (aa) sequence identity with mouse PMVK.

WB, ICC/IF, Flow Cytometry, ELISA

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Chambliss, K. L., Slaughter, C. A., Schreiner, R., Hoffmann, G. F., Gibson, K. M. Molecular cloning of human phosphomevalonate kinase and identification of a consensus peroxisomal targeting sequence. J. Biol. Chem. 271: 17330-17334, 1996. 2. Olivier, L. M., Chambliss, K. L., Gibson, K. M., Krisans, S. K. Characterization of phosphomevalonate kinase: chromosomal localization, regulation, and subcellular targeting. J. Lipid Res. 40: 672-679, 1999. 3. Zhang, Z., Li, C., Wu, F., Ma, R., Luan, J., Yang, F., Liu, W., Wang, L., Zhang, S., Liu, Y., Gu, J., Hua, W., and 13 others. Genomic variations of the mevalonate pathway in porokeratosis. eLife 4: e06322, 2015. Note: Electronic Article. Erratum: eLife 5: e14383, 2016.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A10103

22 kDa

22 kDa

6

IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.