Anti-PNPLA1 Antibody Picoband® 31.0647 Vervoeging

PNPLA1 is important in the formation of the epidermal lipid barrier and plays a role in glycerophospholipid metabolism.

PNPLA1

285848

Q8N8W4

Human

E.coli-derived human PNPLA1 recombinant protein (Position: K141-D496) . Human PNPLA1 shares 51.5% amino acid (aa) sequence identity with mouse PNPLA1.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Ahmad, F., Ansar, M., Mehmood, S., Izoduwa, A., Lee, K., Nasir, A., Abrar, M., Mehmood, S., Ullah, A., Aziz, A., University of Washington Center for Mendelian Genomics, Smith, J. D., Shendure, J., Bamshad, M. J., Nicekrson, D. A., Santos-Cortez, R. L. P., Leal, S. M., Ahmad, W. A novel missense variant in the PNPLA1 gene underlies congenital ichthyosis in three consanguineous families. J. Europ. Acad. Derm. Venereol. 30: e210-e213, 2016. Note: Electronic Article. 2. Boyden, L. M., Craiglow, B. G., Hu, R. H., Zhou, J., Browning, J., Eishenfield, L., Lim, Y. L., Luu, M., Randolph, L. M., Ginarte, M., Fachal, L., Rodriguez-Pazos, L., and 10 others. Phenotypic spectrum of autosomal recessive congenital ichthyosis due to PNPLA1 mutation. Brit. J. Derm. 177: 319-322, 2017. 3. Fachal, L., Rodriguez-Pazos, L., Ginarte, M., Carracedo, A., Toribio, J., Vega, A. Identification of a novel PNPLA1 mutation in a Spanish family with autosomal recessive congenital ichthyosis. (Letter) Brit. J. Derm. 170: 980-982, 2014.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.