Anti-POH1/PSMD14 Antibody Picoband® fluoro488 Vervoeging

26S proteasome non-ATPase regulatory subunit 14, also known as 26S proteasome non-ATPase subunit Rpn11, is an enzyme that in humans is encoded by the PSMD14 gene. This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2.

Semaphorin-3B; Sema A (V) ; Semaphorin-V; Sema V; SEMA3B; SEMA5; SEMAA

PSMD14

10213

O00487

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human POH1/PSMD14 recombinant protein (Position: D21-K310) .

Expressed abundantly but differentially in a variety of neural and nonneural tissues.

Flow Cytometry

Adapters, Coat Proteins, Cytoplasmic, Protein Trafficking, Signal Transduction, Vesicle Transport

Immunogen affinity purified.

Liquid

Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

1. Spataro, V., Toda, T., Craig, R., Seeger, M., Dubiel, W., Harris, A. L., Norbury, C. Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit. J. Biol. Chem. 272: 30470-30475, 1997. 2. Yao, T., Cohen, R. E. A cryptic protease couples deubiquitination and degradation by the proteasome. Nature 419: 403-407, 2002.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

104553 MW

6

Semaphorin 3B

Endoplasmic reticulum. Secreted.

AP-2 complex subunit beta

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.