Anti-POU6F2 Antibody Picoband®

This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Boster Bio Anti-POU6F2 Antibody Picoband® catalog # A10673-2. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

POU6F2; RPF1; POU domain, class 6, transcription factor 2; Retina-derived POU domain factor 1; RPF-1

POU6F2

11281

P78424

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human POU6F2 recombinant protein (Position: E24-Q446) . Human POU6F2 shares 89.7% amino acid (aa) sequence identity with mouse POU6F2.

WB, ELISA

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Gross, M. B. Personal Communication. Baltimore, Md. 4/5/2019. 2. Perotti, D., De Vecchi, G., Testi, M. A., Lualdi, E., Modena, P., Mondini, P., Ravagnani, F., Collini, P., Di Renzo, F., Spreafico, F., Terenziani, M., Sozzi, G., Fossati-Bellani, F., Radice, P. Germline mutations of the POU6F2 gene in Wilms tumors with loss of heterozygosity on chromosome 7p14. Hum. Mutat. 24: 400-407, 2004. 3. Perotti, D., Testi, M. A., Mondini, P., Pilotti, S., Green, E. D., Pession, A., Sozzi, G., Pierotti, M. A., Fossati Bellani, F., Radice, P. Refinement within single yeast artificial chromosome clones of a minimal region commonly deleted on the short arm of chromosome 7 in Wilms tumours. Genes Chromosomes Cancer 31: 42-47, 2001.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A10673-2

73 kDa

73 kDa

POU class 6 homeobox 2

POU domain, class 6, transcription factor 2

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.