Anti-PPIL3 Antibody Picoband® 31.0647 Vervoeging

Peptidyl-prolyl cis-trans isomerase-like 3 is an enzyme that in humans is encoded by the PPIL3 gene. This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Alternative splicing results in multiple transcript variants.

Nck-associated protein 1; NAP 1; Membrane-associated protein HEM-2; p125Nap1; NCKAP1; HEM2, KIAA0587, NAP1

PPIL3

53938

Q9H2H8

Human, Mouse

No cross-reactivity with other proteins.

E.coli-derived human PPIL3 recombinant protein (Position: M1-Q161) .

Expressed in all tissues examined except peripheral blood leukocytes, with highest expression in brain, heart, and skeletal muscle.

Flow Cytometry

Neurogenesis, Neurology Process, Neuroscience, NFKB Pathway, Nuclear Signaling, Signal Transduction, Signaling Pathway

Immunogen affinity purified.

Liquid

Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1.

1. Zhou, Z., Ying, K., Dai, J., Tang, R., Wang, W., Huang, Y., Zhao, W., Xie, Y., Mao, Y. Molecular cloning and characterization of a novel peptidylprolyl isomerase (cyclophilin) -like gene (PPIL3) from human fetal brain. Cytogenet. Cell Genet. 92: 231-236, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

128790 MW

6

Nck-associated protein 1

Cell membrane ; Single-pass membrane protein ; Cytoplasmic side . Cell projection, lamellipodium membrane ; Single-pass membrane protein ; Cytoplasmic side . At the interface between the lamellipodial actin meshwork and the membrane. .

Nck-associated protein 1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.