Anti-PPM1G Antibody Picoband® fluoro550 Vervoeging

Protein phosphatase 1G is an enzyme that in humans is encoded by the PPM1G gene. The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.

Neurocan core protein; Chondroitin sulfate proteoglycan 3; NCAN; CSPG3, NEUR

PPM1G

63977

O15355

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human PPM1G recombinant protein (Position: E48-Q457) .

Brain.

Flow Cytometry

Cell Adhesion Proteins, ECM Proteins, Neuroscience

Immunogen affinity purified.

Liquid

May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM) . Chondroitin sulfate proteoglycan; binds to hyaluronic acid.

1. Gross, M. B. Personal Communication. Baltimore, Md. 9/30/2014. 2. Murray, M. V., Kobayashi, R., Krainer, A. R. The type 2C Ser/Thr phosphatase PP2C-gamma is a pre-mRNA splicing factor. Genes Dev. 13: 87-97, 1999. 3. Travis, S. M., Welsh, M. J. PP2C-gamma: a human protein phosphatase with a unique acidic domain. FEBS Lett. 412: 415-419, 1997.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

104553 MW

6

Neurocan

Secreted .

AP-2 complex subunit beta

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.