Anti-PPP2R5B Antilichaam (C-term)

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues.

Boster Bio Anti-PPP2R5B Antibody (C-term) (Catalog # A09894-1) . Tested in IF, WB application (s) . This antibody reacts with Human.

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform, PP2A B subunit isoform B'-beta, PP2A B subunit isoform B56-beta, PP2A B subunit isoform PR61-beta, PP2A B subunit isoform R5-beta, PPP2R5B

PPP2R5B

Q15173

Human

This PPP2R5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 466-500 amino acids from the C-terminal region of human PPP2R5B.

Highest expression in brain.

IF, WB

Neuroscience, Signal Transduction, Anti-Wnt-Pathway (plus Lgr5) Antibodies

This antibody is purified through a protein A column, followed by peptide affinity purification.

As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09894-1

57393 Da

Cytoplasm.

Rabbit IgG

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.