Anti-PPP4C Antibody Picoband®

Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the PPP4C gene. Enables protein serine/threonine phosphatase activity. Involved in regulation of double-strand break repair via homologous recombination. Located in cytosol; nucleoplasm; and plasma membrane.

Boster Bio Anti-PPP4C Antibody Picoband® catalog # A06390-4. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Rho-related GTP-binding protein Rho6; Rho family GTPase 1; Rnd1; RND1; RHO6

PPP4C

5531

P60510

Human

No cross-reactivity with other proteins.

E.coli-derived human PPP4C recombinant protein (Position: Q13-L307) .

Mostly expressed in brain and liver.

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Actin Assembly, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, G Protein Signaling, Microfilaments, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. .

1. Bastians, H., Krebber, H., Hoheisel, J., Ohl, S., Lichter, P., Ponstingl, H., Joos, S. Assignment of the human serine/threonine protein phosphatase 4 gene (PPP4C) to chromosome 16p11-p12 by fluorescence in situ hybridization. Genomics 42: 181-182, 1997. 2. Brewis, N. D., Cohen, P. T. W. Protein phosphatase X has been highly conserved during mammalian evolution. Biochim. Biophys. Acta 1171: 231-233, 1992. 3. Chen, G. I., Tisayakorn, S., Jorgensen, C., D'Ambrosio, L. M., Goudreault, M., Gingras, A.-C. PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4. J. Biol. Chem. 283: 29273-29284, 2008.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A06390-4

26056 MW

35 kDa

6

Rho-related GTP-binding protein Rho6

Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytoskeleton .

AP-2 complex subunit mu

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.