Anti-PRC1 Konijn Monoklonale Antilichaam

Boster Bio Anti-PRC1 Rabbit Monoclonal Antibody catalog # M00160. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Protein regulator of cytokinesis 1 ; PRC1

PRC1

9055

O43663

Human, Mouse, Rat

A synthesized peptide derived from human PRC1

Clone: EH-16

Overexpressed in bladder cancer cells (PubMed:17409436) . .

WB, IHC, ICC, IF, IP, Flow Cytometry

Cell Biology, Cell Cycle, Cell Division, Cytokinesis

Affinity-chromatography

0.5mg/ml

Liquid

Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00160

71607 MW

72 kDa

Protein regulator of cytokinesis 1

Nucleus . Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Midbody . Colocalized with KIF20B in the nucleus of bladder carcinoma cells at the interphase. Colocalized with KIF20B in bladder carcinoma cells at prophase, metaphase, early anaphase, at the midzone in late anaphase and at the contractile ring in telophase (PubMed:17409436) . Predominantly localized to the nucleus of interphase cells. During mitosis becomes associated with the mitotic spindle poles and localizes with the cell midbody during cytokinesis. .

P2X purinoceptor 1

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.