Anti-PRDM15 Antibody Picoband®

PR/SET domain 15 is a protein that in humans is encoded by the PRDM15 gene. Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II; regulation of signal transduction; and regulation of stem cell division. Located in nuclear body.

Boster Bio Anti-PRDM15 Antibody Picoband® catalog # A13548-1. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

PRDM15

63977

P57071

Human

No cross-reactivity with other proteins

E.coli-derived human PRDM15 recombinant protein (Position: D24-Q1494) .

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

ELISA, Flow Cytometry, IF, IHC, WB

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

1. Mzoughi, S., Zhang, J., Hequet, D., Teo, S. X., Fang, H., Xing, Q. R., Bezzi, M., Seah, M. K. Y., Ong, S. L. M., Shin, E. M., Wollmann, H., Wong, E. S. M., Al-Haddawi, M., Stewart, C. L., Tergaonkar, V., Loh, Y.-H., Dunn, N. R., Messerschmidt, D. M., Guccione, E. PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAP-ERK signaling. Nature Genet. 49: 1354-1363, 2017. 2. Shibuya, K., Kudoh, J., Okui, M., Shimizu, N. Identification of a novel zinc finger protein gene (ZNF298) in the GAP2 of human chromosome 21q. Biochem. Biophys. Res. Commun. 332: 557-568, 2005.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A13548-1

64099 MW

169 kDa

6

RNA-binding protein 47

Nucleus .

Follicular dendritic cell secreted peptide

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.