Anti-PRKCSH Antibody Picoband® fluoro488 Vervoeging

Glucosidase 2 subunit beta is an enzyme that in humans is encoded by the PRKCSH gene. This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.

Fms-related tyrosine kinase 3 ligand ; Flt3lg

PRKCSH

5589

P14314

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human PRKCSH recombinant protein (Position: E16-L506) .

Flow Cytometry

Angiogenesis, Cardiovascular, Cytokines, Immunology, Innate Immunity

Immunogen affinity purified.

Liquid

1. Cornec-Le Gall, E., Torres, V. E., Harris, P. C. Genetic complexity of autosomal dominant polycystic kidney and liver diseases. J. Am. Soc. Nephrol. 29: 13-23, 2018. 2. Drenth, J. P. H., te Morsche, R. H. M., Smink, R., Bonifacino, J. S., Jansen, J. B. M. J. Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease. Nature Genet. 33: 345-348, 2003. 3. Fedeles, S. V., Tian, X., Gallagher, A.-R., Mitobe, M., Nishio, S., Lee, S. H., Cai, Y., Geng, L., Crews, C. M., Somlo, S. A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nature Genet. 43: 639-647, 2011.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

25847 MW

6

Fms-related tyrosine kinase 3 ligand

Uncharacterized protein

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.