Anti-PRPF31 Antibody Picoband®

PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae), also known as PRPF31, is a protein which in humans is encoded by the PRPF31 gene. This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

Boster Bio Anti-PRPF31 Antibody Picoband® catalog # A03137-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Tumor necrosis factor receptor superfamily member 18; Glucocorticoid-induced TNFR-related protein; CD357; Tnfrsf18; Gitr

PRPF31

26121

Q8WWY3

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human PRPF31 recombinant protein (Position: K73-K488) .

Detected in thymus and in activated splenocytes.

WB, ICC, IF, Flow Cytometry, ELISA

Adaptive Immunity, Cancer, Cytokines, Growth Factors, Growth Factors/Hormones, Immunology, Innate Immunity, Signal Transduction

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

1. Al-Maghtheh, M., Vithana, E., Tarttelin, E., Jay, M., Evans, K., Moore, T., Bhattacharya, S., Inglehearn, C. F. Evidence for a major retinitis pigmentosa locus on 19q13.4 (RP11), and association with a unique bimodal expressivity phenotype. Am. J. Hum. Genet. 59: 864-871, 1996. 2. Berson, E. L., Gouras, P., Gunkel, R. D., Myrianthopoulos, N. C. Dominant retinitis pigmentosa with reduced penetrance. Arch. Ophthal. 81: 226-234, 1969. 3. Deery, E. C., Vithana, E. N., Newbold, R. J., Gallon, V. A., Bhattacharya, S. S., Warren, M. J., Hunt, D. M., Wilkie, S. E. Disease mechanism for retinitis pigmentosa (RP11) caused by mutations in the splicing factor gene PRPF31. Hum. Molec. Genet. 11: 3209-3219, 2002.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A03137-1

26000 MW

60 kDa

6

Tumor necrosis factor receptor superfamily, member 18

Cell membrane. Single-pass type I membrane protein. Secreted.

Transcription factor E2F3

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.