Anti-PSAT1 Antibody Picoband® 31.0550 Vervoeging

Phosphoserine aminotransferase (PSA), also known as phosphohydroxythreonine aminotransferase (PSAT), is an enzyme that in humans is encoded by the PSAT1 gene. This gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants.

ELAV-like protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1; ELAVL2; HUB

PSAT1

29968

Q9Y617

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human PSAT1 recombinant protein (Position: M1-K363) .

Brain; neural-specific.

Flow Cytometry

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing

Immunogen affinity purified.

Liquid

Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.

1. Hart CE, Race V, Achouri Y, Wiame E, Sharrard M, Olpin SE, Watkinson J, Bonham JR, Jaeken J, Matthijs G, Van Schaftingen E (2007) . Phosphoserine aminotransferase deficiency: a novel disorder of the serine biosynthesis pathway. Am. J. Hum. Genet. 80 (5) : 931–7. 2. Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A (2011) . A conditional knockout resource for the genome-wide study of mouse gene function. Nature 474 (7351) : 337–342.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

49655 MW

6

ELAV like RNA binding protein 2

Cytoplasm. Nucleus. Cytoplasm.

AP-2 complex subunit mu

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.