Anti-PSD2 Antibody Picoband® 31.0550 Vervoeging

Predicted to enable guanyl-nucleotide exchange factor activity and phospholipid binding activity. Predicted to be involved in regulation of ARF protein signal transduction and regulation of catalytic activity. Predicted to be located in cleavage furrow and ruffle membrane. Predicted to be active in glutamatergic synapse and postsynapse.

Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/I; Histone H3/j; Histone H3/k; Histone H3/l; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; H3FJ

PSD2

84249

Q9BQI7

Human

No cross-reactivity with other proteins.

E.coli-derived human PSD2 recombinant protein (Position: G70-H756) .

Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Flow Cytometry

DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling, RNA Processing

Immunogen affinity purified.

Liquid

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

1. Yu, L. , Dawe, R. J. , Boyle, P. A. , Gaiteri, C. , Yang, J. , & Buchman, A. S. , et al. (2017) . Association between brain gene expression, dna methylation, and alteration of ex vivo magnetic resonance imaging transverse relaxation in late-life cognitive decline. Jama Neurol. 2. Kunkle, Brian, W. , Vardarajan, Badri, N. , Adam, C. , & Whitehead, et al. Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport. 3. Cannavo, E. , Gerrits, B. , Marra, G. , Schlapbach, R. , & Jiricny, J. . (2007) . Characterization of the interactome of the human mutl homologues mlh1, pms1, and pms2. Journal of Biological Chemistry, 282 (5), 2976-2986.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Histone cluster 1 H3 family member a/b/c/d/e/f/g/h/i/j

Cytoplasm.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.