Anti-PSMD5 Antibody Picoband® PE Vervoeging

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.

PSMD5; KIAA0072; 26S proteasome non-ATPase regulatory subunit 5; 26S protease subunit S5 basic; 26S proteasome subunit S5B

PSMD5

5711

Q16401

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human PSMD5 recombinant protein (Position: M1-K493) . Human PSMD5 shares 90.1% amino acid (aa) sequence identity with mouse PSMD5.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Deveraux, Q., Jensen, C., Rechsteiner, M. Molecular cloning and expression of a 26 S protease subunit enriched in dileucine repeats. J. Biol. Chem. 270: 23726-23729, 1995. 2. Deveraux, Q., Ustrell, V., Pickart, C., Rechsteiner, M. A 26 S protease subunit that binds ubiquitin conjugates. J. Biol. Chem. 269: 7059-7061, 1994. 3. Nomura, N., Nagase, T., Miyajima, N., Sazuka, T., Tanaka, A., Sato, S., Seki, N., Kawarabayasi, Y., Ishikawa, K., Tabata, S. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 1: 223-229, 1994.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

56 kDa

6

Proteasome 26S subunit, non-ATPase 5

26S proteasome non-ATPase regulatory subunit 5

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.